Preventing Sterile Vial Glass Breakage: From Cause to Solution
Sterile glass vial breakage remains one of the most persistent challenges in pharmaceutical manufacturing. Every broken vial means wasted product, downtime, and higher costs, while also raising patient safety concerns. Breakage can stem from mechanical impact, thermal stress, or inherent material defects. The good news: with the right combination of equipment upgrades, material selection, handling […]
Container Closure Integrity – Challenge for Injectables
For injectable products, assuring the integrity of the container closure system (CCS) and container closure integrity is fundamental to safeguarding product quality and patient safety over the entire shelf life. Developing an inherently robust CCS is an iterative process—guided by an understanding of product stability, manufacturing methods, and anticipated distribution and storage conditions. Product protection […]
Pharma Production Line Optimization Reduces Downtime By 49% For Sanofi
It’s usually the small changes that lead to big results and pharma giant Sanofi proved this with its pharma production line optimization project. The company’s use of SmartSkin technology for this project at their Waterford plant in Ireland resulted in a massive reduction in downtime and an improvement in yield. Here’s what Sanofi did. Production […]
Rethinking Data Analytics in the Pharmaceutical Industry: Turning Information Into Action
Data analytics in the pharmaceutical industry is evolving from being a compliance and reporting tool to playing a strategic role in helping take informed decisions. When used correctly, data analysis can play a big role in taking operational decisions, preventing time overruns, reducing quality related issues and unlocking Overall Equipment Efficiency (OEE) in the pharma […]
Mastering PET Bottle Manufacturing: Challenges and Line Optimization Strategies
PET (Polyethylene Terephthalate) dominates beverage packaging for good reason—it's clear, lightweight, durable, recyclable and therefore very economical. While there are other container formats available, seasoned manufacturers know the real challenge is not in the material itself, but in the complex, fast-paced production environment it demands. What Is PET and Why It Dominates Beverage Packaging PET […]
Can Seamer Maintenance for Common Defects – How to Avoid Downtime
In high-speed beverage production, seamers are a crucial part of the manufacturing process and where can quality is tested the most. These machines form an hermetic seal with the end and can then send the seamed can away down the line. Unchecked issues with seaming equipment can lead to a variety of can defects that […]