On-Demand
Seal Tightness Digital Container Twins to Support Container Closure Integrity Assurance
ISPE Aseptic Conference 2024
A novel method for monitoring vial sealing and container handling using sensor-enabled digital container twins that measure seal force, pressure, and shock will be explained. This new technology gives insights into the process variability inherent in the capping and crimping process and throughout the filling and packaging process. Data will be shared that focuses on the interrelationships of components and crimping performance. Anticipated applications will be presented including data generated that gives insights into material properties and how they impact seal tightness.